10 results
Causes of Neutropenia with Pancytopenia - Differential Diagnosis Algorithm
Sequestration:
 • Splenomegaly
Marrow Infiltration:
 • Hematologic and non-hematologic
Neutropenia with Pancytopenia ... - Differential ... Toxins • Aplastic Anemia ... Myelodysplasia Nutritional ... deficiency: • B12
Pancytopenia - Differential Diagnosis

Congenital Diseases:
• GATA2 deficiency
• Fanconi’s anemia
• Wiskott-Aldrich syndrome
• Ribosomopathy or telomeropathy

Cancer:
• Leukemia
• Lymphoma

Inflammatory
Pancytopenia - Differential ... deficiency • Fanconi’s anemia ... Wiskott-Aldrich syndrome ... consumption • Vitamin B12 ... Diagnosis #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
and Differential ... HLH syndrome 5. ... Drugs Nutritional ... Acquired Aplastic Anemia ... Diagnosis #Algorithm #Hematology
Pancytopenia - Workup and Differential Diagnosis Algorithm
Consumption Disorders
 1. Autoimmune Mediated Pancytopenia
 2. Splenic Sequestration
Peripheral Destruction
and Differential ... HLH syndrome 5 ... Drugs Nutritional ... Acquired Aplastic Anemia ... Diagnosis #Algorithm #Hematology
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
Clinically Important ... Wernicke-Korsakoff syndrome ... gestation • Vitamin B12 ... Vitamins #Deficiency #differential ... signs #symptoms #nutrition
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
bone marrow + pancytopenia ... Clinical Presentation ... • Peripheral Pancytopenia ... Treatment: ... #oncology #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Platelet Disorders • Nutritional ... : vitamin B12 or ... factor (GCSF) treatments ... blood count with differential ... #diagnosis #hematology
Etiologies of Vitamin B12 Deficiency
 • Inadequate intake - Rare but seen in very strict vegans
autoantibodies (pernicious anemia ... malabsorption syndromes ... VitaminB12 #deficiency #differential ... #diagnosis #hematology ... #nutrition
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... (Clinical Dx). ... oral ulcers in 12 ... Behcet disease) Differential ... Arthritis, AS Treatment
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... perfusion - shock->treatments ... before beginning treatment ... - Compartment syndrome ... 30mmHg) - Severe anemia