47 results
VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome
Clinical Syndrome:
 • Common Clinical Features: alveolitis, ear and
Clinical Syndrome ... : • Common Clinical ... nose chondritis, skin ... Abnormalities: macrocytic anemia ... polyarteritis nodosa (12%
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... purple, hemorrhagic skin ... - Hemolytic anemia ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... Headaches • Pale skin ... Treatment: ... #oncology #hematology ... #diagnosis #management
Behcet's Syndrome - Diagnosis
Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease):
 • Recurrent,
- Diagnosis Diagnostic ... episodes within a 12 ... vasculitis - Skin ... test Most Common Clinical ... Wide variety of skin
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
Nikolsky's sign is a clinical ... syndrome, caused ... differentiating between the diagnosis ... #PhysicalExam # ... Video #Clinical
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
, Dry coarse skin ... Carpal timel syndrome ... Myotonia, Muscular ... Signs #Symptoms #Diagnosis ... #PhysicalExam #
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
intrinsic factor, IF) Clinical ... , yellow skin, cognitive ... palpitations), skin ... Check for IF ab Treatment ... consider other diagnosis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... and diplopia) • Vascular ... (Clinical Dx). ... oral ulcers in 12 ... Arthritis, AS Treatment
Sarcoidosis - Skin Manifestations

This is a quick overview of some of the cutaneous manifestations of sarcoidosis.
Sarcoidosis - Skin ... Lupus Pernio • Macular ... #Sarcoidosis #diagnosis ... #clinical #differential ... #treatment #photo
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Differential #Diagnosis