13 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
disorders • Diagnosis ... #HES #Hematology ... #eosinophilia # ... eosinophils #diagnosis ... #management #algorithm
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... (HES) - Diagnosis ... and Management ... #diagnosis #hematology ... #differential #management
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
Criteria for Diagnosis ... Exanthematous Pustulosis Management ... SinaiBmoreIMRes #DRESS #Syndrome ... #dermatology #diagnosis ... #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... - Hepatitis, eosinophilic ... • Reticulocyte index ... Anemia #oncology #hematology ... #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... hyperviscosity syndrome ... Non calcium phos binders ... #TLS #diagnosis ... #management #hematology
Pustular Skin Lesions - Differential Diagnosis Framework

What are pustules?
• Pustules < 5-10 mm + pus
• Material
- Differential Diagnosis ... Mpox • Starts ... SAPHO syndrome ( ... Eosinophilic folliculitis ... #Dermatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Pinpoint-sized red spots ... appears abnormal under ... appear abnormal under ... look abnormal under ... #diagnosis #hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
anterior chest wall, parts ... lower-extremity joints Diagnosis ... • A clinical diagnosis ... #Rheumatology #diagnosis ... #management #Dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
• 75% usually under ... • (Peripheral eosinophilia ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Oncology #Diagnosis
Hamartomatous Polyposis Syndromes - Peutz-Jeghers Syndrome (PJS), Juvenile Polyposis Syndrome (JPS), Cowden Syndrome (CS), Cronkhite-Canada (CC),
Peutz-Jeghers Syndrome ... (PJS): - "Spots ... pigmentation, spots ... cross vermillion border ... #diagnosis #management