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diagnosis hyperkalemia differential causes nephrology management pharmacology antiarrhythmics cardiology pathophysiology treatment achalasia antiarrhythmic clinicopathology evaluation gastroenterology guidelines hypokalemia intercellularshift laboratory
Antiarrhythmic Medications - Vaughan Williams Classification - Summary Table Class I agents - Sodium Channel Blockers⠀ Class II
- Summary Table ... are beta blockers ... - Potassium Channel ... Blockers Class ... #Summary #Table
Antiarrhythmics - Vaughan Williams Classification: CLASS 1 - Sodium Channel Blockers: • MOA: Block fast Na+ channels
Vaughan Williams Classification ... 2 - Beta Blockers ... 3 - Potassium Channel ... alpha & beta adrenergic ... #Pharmacology #Classification
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
phlebotomy High ... • NSAIDs • ACE ... • Recent IV potassium ... • Beta blockers ... #potassium #high
The Diagnostic Approach to Hyperkalemia Drugs - Amiloride - Spironolactone - Triamterene - Trimethoprim - Pentamidine -
inhibitors Other causes ... transplant - SLE High ... LMW heparin - ACE-I ... - NSAlDs - Beta-Blockers ... #Hyperkalemia #Algorithm
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
phlebotomy High ... • NSAIDs • ACE ... • Recent IV potassium ... • Beta blockers ... #potassium #high
Antiarrhythmics Pharmacology Summary Cardiac Conduction Phases: Phase 0 - Ventricular Depolarization: • Na+ channels open leading to a
Vaughan Williams Classification ... 2 - Beta Blockers ... 3 - Potassium Channel ... alpha & beta adrenergic ... #Pharmacology #Classification
Hyperkalemia - Management Algorithm • IV calcium • IV insulin and glucose and/or salbutamolt • Consider
Hyperkalemia - Management Algorithm ... Dialysis Serum potassium ... and ECG changes ... #high #diagnosis ... #management #algorithm
Emergent Hyperkalemia Treatment Algorithm ECG changes, weakness, K+ >6.5 Or renal insufficiency with K >5.5 with cellular
Hyperkalemia Treatment Algorithm ... bradycardia, AV blocks ... Combo of insulin + beta-agonist ... glucose <100 • Beta-agonist ... treatment Remove potassium
Causes of Hyperkalemia - Reduced Excretion - Differential Diagnosis Algorithm Reduced flow through distal nephron - TTKG
Differential Diagnosis Algorithm ... • ENaC blockers ... nephropathy • Beta ... Differential #Diagnosis #Algorithm ... #Causes
Causes of Hyperkalemia l. Pseudohyperkalemia A Cellular efflux; thrombocytosis, erythrocytosis, leukocytosis, in vitro hemolysis B.
Causes of Hyperkalemia ... Beta-Adrenergic ... Differential #Diagnosis #High ... #Potassium #Classification ... #Causes
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