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diagnosis differential hepatology cardiology management pbc pruritus antiarrhythmics cholangitis cirrhosis classes criticalcare dermatology infectiousdiseases injury jaundice liver pharmacology workup abdominal
Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
Primary Biliary ... Cirrhosis - Pathophysiology ... gradual loss of bile ... Cholestasis #PBC #Primary ... #Pathophysiology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... 65 years PBC Pathophysiology ... ducts causes cholestasis ... No extrahepatic biliary ... #Biliary #Cirrhosis
Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of ... genes coding for bile ... miscellaneous causes ... #Jaundice #Classification ... #differential #causes
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Differential Diagnosis Algorithm ... Intestine - Other causes ... - Drugs - Primary ... biliary Cholangitis ... diseases/Bile duct
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Differential Diagnosis Algorithm ... Malignant • Primary ... Biliary Cirrhosis ... Differential #Diagnosis #Algorithm ... #Causes #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Differential Diagnosis Algorithm ... US - Dilated Bile ... Duct Stone • Biliary ... Differential #Diagnosis #Algorithm ... #Causes
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Differential Diagnosis Algorithm ... on Ultrasound Biliary ... Gallstones • Biliary ... Cholangiocarcinoma • Primary ... #Causes #Hepatology
Causes of Ascites - Differential Diagnosis Algorithm Portal Hypertension - Prehepatic: • Portal vein thrombosis • Splenic
Causes of Ascites ... Differential Diagnosis Algorithm ... liver failure • Primary ... biliary cholangitis ... • Primary sclerosing
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis Algorithm ... Causes == Primary ... • Arthropod bites ... Differential #Diagnosis #Algorithm ... #causes
Bronchiectasis: diagnosis and management Causes of localized -> diffuse bronchiectasis Foreign body, Bronchial stenosis (tumor, .. ),
management Causes ... Cystic fibrosis, primary ... ciliary, dyskinesia ... Differential #workup #algorithm
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