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management hematology differential pathophysiology syndrome neurology algorithm infections infectiousdiseases leukemia rheumatology tb vasculitis workup activetb anemia aplastic chronic classification dermatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... ALL Symptoms: ... ) CLL Symptoms: ... Leukemia #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... with no early symptoms ... Physical Exam/Signs ... microglobulin Treatment ... #workup #oncology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Autoimmune diseases • Clinical ... Hepatosplenomegaly, cytopenias(bleeding ... Differential Diagnosis ... Tumors • Tuberculosis ... NonHodgkins #comparison #oncology
Pott's Disease in Tuberculosis - Diagnosis and Management Summary Epidemiology: - Typically from TB endemic areas -
extrapulmonary cases Clinical ... Signs/Symptoms: ... years - May have signs ... pulmonary TB PE ... should be done in ALL
Sarcoidosis Non-caseating granulomas (Composed of T-helper & inflammatory cells) Clinical: • Disease fatal in 10% of
) Clinical: ... polyarthritis • Pulmonary ... #Sarcoidosis #Diagnosis ... #Symptoms #Signs ... #Pulmonary
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... lymphocytes, smudge cells ... immunophenotype Clinical ... uw_IMresidency #CLL ... Lymphocytic #Leukemia #oncology
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Pathogenesis and clinical ... cells -> Mutagenic ... Retinoblastoma Signs ... ophthalmology #diagnosis ... #signs #symptoms
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... neutropenia • Mucosal bleeding ... Symptomatic anemia Diagnosis ... Consider stem cell
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
involvement - seeding ... characteristic features Clinical ... Diagnosis: Latent ... Treatment: Active ... #TB #Diagnosis
Diagnostic Algorithm for Suspected Pulmonary Embolism Well's Criteria for PE • Clinical Signs and Symptoms of DVT
Diagnostic Algorithm ... for Suspected Pulmonary ... Embolism Well's ... Criteria for PE • Clinical ... Signs and Symptoms
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