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diagnosis algorithm management anticoagulation malignancy vte anemia aplastic chemotherapy chronic cll cyp3a4 emergencies hemeonc inducers inhibitors interactions lymphocytic mds myelodysplasia
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis. Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... of cancer-associated ... thrombosis; PE = pulmonary ... Anticoagulation #Management #Hematology ... #Oncology
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 Treatment algorithm for VTE in Malignancy (A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
thrombosis in cancer ... DOAC, direct oral ... #DOAC #VTE #Malignancy ... Anticoagulation #Management #Hematology ... #Oncology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
) Cancer-treatment ... thereby leading ... metabolization leading ... #Chemotherapy #Oncology ... #Hematology #Interactions
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Symptoms: • Malaise, bleeding ... night sweats, bleeding ... • Significant bleeding ... lymphoid organs When Cancer ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
- Summary Cancer ... or basket cells ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... virus (EBV) • Leukemia ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... are caused by bleeding ... • Hairy Cell Leukemia ... Syndromes #diagnosis #hematology ... #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
syndrome): - Hematologic ... Simultaneous clotting and bleeding ... Usually myeloid leukemias ... “big & sticky” cells ... renal failure, pulmonary
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
syndromes current treatment ... acute myeloid leukemia ... cardiovascular or pulmonary ... an infection or bleeding ... #algorithm #hematology
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