30 results
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Hyperviscosity Syndrome ... • Spontaneous bleeding ... neutrophil count < 500 cells ... Superior Vena Cava Syndrome ... : Tumor Lysis Syndrome
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... old, ~10,000 new cases ... only curative treatment ... #hematology #oncology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... by bleeding (petechiae ... factor (GCSF) treatments ... marrow studies Treatment ... diagnosis #hematology #oncology
Fat Embolism Syndrome
Trauma to the long bone or pelvis accounts for —9096 of cases. The diagnosis
Fat Embolism Syndrome ... the long bone or pelvis ... accounts for —9096 of cases ... onset widespread pulmonary ... #Diagnosis #Signs
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... ecchymoses, mucosal bleeding ... and petechiae Causes ... aplastic anemia Treatment ... Aplastic #Anemia #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Symptoms: • Malaise, bleeding ... -> AML: Blast crises ... develop leukostasis syndrome ... • Tumor lysis syndrome ... Leukemia #Hematology #Oncology
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... maintained fever CAUSES ... hyperthermia crisis (late sign ... amphetamines) Toxic: • Radiologic ... #Differential #Causes
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Refeeding Syndrome ... PO4& Mg prior to feeding ... - CHF - Pulmonary ... PO4 and Mg into cells ... pathophysiology #symptoms #signs
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Syndromes - OnePager ... Renal Syndromes ... Goodpasture's cause ... leading to diffuse ... diagnosis #management #treatment
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... WBC >100k, + lab signs ... organ damage • Treatment ... Lysis of tumor cells ... Low calcium • Treatment