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Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
that are poorly formed ... unusual bruising or bleeding ... are caused by bleeding ... • Hairy Cell Leukemia ... diagnosis #hematology #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... ecchymoses, mucosal bleeding ... virus (EBV) • Leukemia ... aplastic anemia Treatment ... Aplastic #Anemia #oncology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
Simultaneous clotting and bleeding ... interventional radiology ... Usually myeloid leukemias ... “big & sticky” cells ... renal failure, pulmonary
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
with presence of pulmonary ... acute coronary syndrome ... #differential #algorithm ... #management #cardiology ... #foamed #heartfailure
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
current treatment ... algorithm 2018. ... acute myeloid leukemia ... cardiovascular or pulmonary ... an infection or bleeding