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Acid Base Disorders - Formulas for appropriate metabolic and respiratory compensation

- Dr Amith Sreedharan - Consultant
Acid Base Disorders ... for appropriate metabolic ... #Acidosis #Alkalosis ... #Compensation # ... Winters #Diagnosis #Nephrology
Acid-Base Disorders - Differential Diagnosis Framework

 • Respiratory Acidosis
 • Respiratory Alkalosis
 • Metabolic Acidosis
 •
Acid-Base Disorders ... - Differential ... • Metabolic Alkalosis ... #Disorders #nephrology ... #differential #
Acid-Base Disorders - Differential Diagnosis Algorithm
Acidemia (pH < 7.35)
 • Metabolic Acidosis (HCO3 < 24mmol/L) CO2
Acid-Base Disorders ... - Differential ... Alkalosis (HCO3 ... #Differential # ... Algorithm #Causes #Compensation
Approach to Acid Base Disorders - Evaluation and Differential Diagnosis
1) Start with the Anion Gap (AG).
2)
Disorders - Evaluation ... and Differential ... chronic) of the disorder ... the appropriate compensation ... Differential Diagnosis
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Acid Base Disorders ... D-lactate (short bowel syndrome ... #AcidBase #disorders ... Diagnosis #Summary #Nephrology ... bloodgas #Acid #Base
Acid Base Disorders Worksheet

Step 1: Gather the necessary data (Na+, CI-, HCO3-, PH, pCO2). Preferably, all
Acid Base Disorders ... is metabolic; If ... patient's acidosis is metabolic ... by failure of compensation ... #diagnosis #differential
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Metabolic Alkalosis ... poisoning Normal acid-base ... #Metabolic #Alkalosis ... urine #Algorithm #nephrology ... #differential #
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
resistance • Metabolic ... alkalosis • Familial ... with specific bleeding ... disorders Vasopressin ... Excretion #Diuresis #Nephrology
Differential Diagnosis of Respiratory Acid-Base Disorders
Alkalosis
A. Central nervous system stimulation: Pain, Anxiety, psychosis, Fever, Cerebrovascular accident,
Differential Diagnosis ... Respiratory Acid-Base ... Disorders Alkalosis ... Recovery from metabolic ... respiratory distress syndrome