17 results
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Fibrinolysis → End ... organ damage Clinical ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic anemia ... DIC is a clinical ... and laboratory diagnosis ... count, D-dimer, egg ... #Hematology #Pathology
Mallet Finger
Absence of a fracture does NOT exclude Mallet finger, the extension function of the DIP
joint needs to be clinically ... Finger deformity caused ... Avulsion fracture • ED ... PIP joint • Ortho ... Radiology #XRay #Diagnosis
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... ecchymoses, mucosal bleeding ... and petechiae Causes ... #oncology #hematology ... #diagnosis #management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... - infiltrates (anemia ... Fibrinolysis & DIC ... #Leukemia #Hematology ... #Oncology #Diagnosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Hepatosplenomegaly, cytopenias(bleeding ... Differential Diagnosis ... Malignancies (eg ... NonHodgkins #comparison #oncology ... #hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
fever syndromes Clinical ... Fever is the main clinical ... purpura to mucosal bleeding ... with leukopenia, anemia ... Activation #Syndrome #Diagnosis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... by bleeding (petechiae ... Out Secondary Causes ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Paradoxical spontaneous bleeding ... : • + Clinical ... cryoglobulins • Negative causes ... skin necrosis • DIC ... hematology
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
invasive procedures/ bleeding ... the Journal of Clinical ... reasoning during clinical ... It's time to end ... other than GI bleeding