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management anemia activation aplastic causes cell classification coagulation comparison cryofibrinogenemia cryoglobulinemia cryoglobulins differential disseminated hemolytic hodgkins intravascular leukemia lymphoma macrophage
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Intravascular Coagulation (DIC ... Fibrinolysis → End ... organ damage Clinical ... #Coagulation #diagnosis ... treatment #management #hematology
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
DIC is a clinical ... and laboratory diagnosis ... count, D-dimer, egg ... hemolytic #anemia #Hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Hepatosplenomegaly, cytopenias(bleeding ... Differential Diagnosis ... Malignancies (eg ... NonHodgkins #comparison #oncology ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Symptoms: • Malaise, bleeding ... night sweats, bleeding ... Fibrinolysis & DIC ... #Leukemia #Hematology ... #Oncology #Diagnosis
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Paradoxical spontaneous bleeding ... : • + Clinical ... skin necrosis • DIC ... #rheumatology # ... hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Fever is the main clinical ... purpura to mucosal bleeding ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... ecchymoses, mucosal bleeding ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... Syndrome: • Clinical ... Labs/Diagnosis: ... Cryoglobulins #diagnosis ... classification #rheumatology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
plasmacytoma) Clinical ... Diagnosis? ... patients with EMD ... #Plasmacytoma #Oncology ... #Hematology
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