14 results
Disorders of the Hepatic and Mesenteric Circulation

Platelets in Cirrhosis
Hypercoagulability in Cirrhosis
Bleeding in Cirrhosis
Portal Vein Thrombosis (PVT)
Mesenteric
in Cirrhosis Bleeding ... Circulation #Disorders #Hepatology ... #Gastroenterology
Oncologic Emergencies - Differential Diagnosis Framework

HEMATOLOGIC ONCOLOGIC EMERGENCIES:
Hyperviscosity Syndrome:
 • Spontaneous bleeding
 • Shortness of breath
Oncologic Emergencies ... Diagnosis Framework HEMATOLOGIC ... ONCOLOGIC EMERGENCIES ... • Spontaneous bleeding ... STRUCTURAL ONCOLOGIC
Diagnostic criteria for Neutropenic Enterocolitis (NEC)
Major Criteria:
 • Neutropenia (ANC <500 x 10^9 cells/L)
 • Bowel
Diarrhea • Lower Gl bleeding ... Diagnosis #criteria #hematology ... #oncology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Leukemia - History of Bleeding ... Algorithm #Causes #Hematology ... #Oncology
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
at high risk of bleeding ... interactions and bleeding ... recurrent VTE and bleeding ... Anticoagulation #Management #Hematology ... #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Symptoms: • Malaise, bleeding ... night sweats, bleeding ... • Significant bleeding ... #Leukemia #Hematology ... #Oncology #Diagnosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Hepatosplenomegaly, cytopenias(bleeding ... Lymphomas • Other hematologic ... NonHodgkins #comparison #oncology ... #differential #hematology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
DOACs thereby leading ... metabolization leading ... #Chemotherapy #Oncology ... #Hematology #Interactions
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
ecchymoses, mucosal bleeding ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Transhepatic Intrajugular Portosystemic Shunt (TIPS) 
Indications:
 • Ascites / Hepatic Hydrothorax
 • Variceal Bleeding
Cardiopulmonary, Renal, and
Hydrothorax • Variceal Bleeding ... Portosystemic #Shunt #Hepatology ... #Gastroenterology