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management hemophagocytic lymphohistiocytosis oncology rheumatology algorithm cancer cell classification crisis criteria hemolytic hodgkins lymphoma macrophage maha mas microangiopathic microscopy nephrology
Hemophagocytic Lymphohistiocytosis (HLH) Clinical Features: Fever, Splenomegaly, Hepatomegaly, Lymphadenopathy, Confusion Classic lab findings in HLH: ↑↑ ferritin, Anemia,
) Clinical Features ... : ↑↑ ferritin, Anemia ... d-dimer, ↓ NK cell ... (affecting 2 2 cell ... #hematology #criteria
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... excessive macrophage activation ... Diagnosis via genetic ... Low or absent NK cell ... management #treatment #hematology
Peripheral blood findings in microangiopathic hemolytic anemia. DIC is a clinical and laboratory diagnosis, not
microangiopathic hemolytic anemia ... DIC is a clinical ... and laboratory diagnosis ... non-specific red cell ... #Hematology #Pathology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... purpura to mucosal bleeding ... with leukopenia, anemia ... #Syndrome #Diagnosis ... #Management #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... Hodgkin Lymphoma - Clinical ... Weight loss • Anemia ... Immune hemolytic anemia ... classification #hematology
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
Crisis (SRC) Clinical ... microangiopathic hemolytic anemia ... activation, ↓ perfusion ... rule out other pathology ... Renal #Crisis #rheumatology
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
plasmacytoma) Clinical ... Diagnosis? ... • No CRAB - no anemia ... IFE, FLC assay Pathology ... #Workup #Hematology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
median age at diagnosis ... disease tolerate anemia ... an infection or bleeding ... importance of clinical ... #algorithm #hematology
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