46 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically ... suspect underlying hematologic ... disorders • Diagnosis ... #HES #Hematology ... #eosinophils #diagnosis
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear ... #Microscopy #Hematology
Idiopathic Thrombocytopenic Purpura 
Clinical:
 • Gingival 
 • Menorrhagia 
 • GI bleeding 
 • Intracranial
Thrombocytopenic Purpura Clinical ... Menorrhagia • GI bleeding ... only for severe bleeding ... Thrombocytopenia #Diagnosis ... #Overview #Hematology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
Bleeding risk calculators ... studies suggest net clinical ... with very high bleeding ... Anticoagulation #Factors #Hematology ... #Diagnosis
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
common inherited bleeding ... disorder Clinical ... • Prolonged bleeding ... VonWillebrand #Disease #Diagnosis ... #Hematology
Nail Findings & Associated Conditions
Change in color, texture, or shape can be harmless, but may suggest
• Green Nail Syndrome ... • Yellow Nail Syndrome ... Nail #fingernail #pathology ... #differential #diagnosis ... #dermatology #nails
Nail Findings & Associated Conditions
Change in color, texture, or shape can be harmless, but may suggest
• Green Nail Syndrome ... • Yellow Nail Syndrome ... Nail #fingernail #pathology ... #differential #diagnosis ... #dermatology #nails
Seborrheic keratosis 
 - Well-circumscribed, stuck-on appearance 
 - Waxy texture 
 - Verrucous surface
rapid growth, or bleeding ... Seborrheic #Keratosis #Dermatology ... #Diagnosis #Benign ... #Clinical #Photo
Chondrodermatitis nodularis 
 - Scaly papule on ear, usually helix 
 - Painful, especially when sleeping
especially when sleeping ... Chondrodermatitis #Nodularis #Dermatology ... #Diagnosis #Benign ... #Clinical #Photo
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
Nikolsky's sign is a clinical ... differentiating between the diagnosis ... Nikolskys #Sign #TEN #Dermatology ... #PhysicalExam #Video ... #Clinical #SJS