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algorithm anemia oncology causes disorders management rheumatology activation anticoagulation aplastic bariatric bypass calculators cancer comparison complications deficiency erythematosus factors folate
Approach to Leukocytosis - Differential Diagnosis Algorithm Features of hematologic malignancy: • Symptoms: B-symptoms, bruising/bleeding, fatigue/weakness, immunosuppression
Leukocytosis - Differential ... Diagnosis Algorithm ... B-symptoms, bruising/bleeding ... Matthew Ho, MD ... #hematology #WBC
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients) Important notes: • No
Bleeding risk calculators ... studies suggest net clinical ... #Risk #Scores # ... Anticoagulation #Factors #Hematology ... #Diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... - History of bleeding ... menstrual - Recent procedures ... Infection exposure (l MD ... #Workup #hematology
Petechiae on Physical Exam Pinpoint, round spots that appear on the skin as a result of microscopic
Pinpoint, round spots ... of microscopic bleeding ... #PhysicalExam #dermatology ... #foot #skin #clinical ... #video
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 Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Autoimmune diseases • Clinical ... Hepatosplenomegaly, cytopenias(bleeding ... Diagnosis of B-Symptoms ... #differential # ... hematology
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
interfered with leading ... mobilize folate stores ... depleted tissue stores ... deficiency #FolicAcid #differential ... #diagnosis #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
fever syndromes Clinical ... Fever is the main clinical ... purpura to mucosal bleeding ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia Clinical ... ecchymoses, mucosal bleeding ... Hypocellular/Hypoplastic MDS ... Anemia #oncology #hematology ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... Pinpoint-sized red spots ... blood count with differential ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
Helpful Clinical Features in Evaluating Bleeding Disorders Age of onset • Neonate - in 20% of haemophilias,
Helpful Clinical ... in Evaluating Bleeding ... Previous surgical procedures ... peds #pediatrics #diagnosis ... #hematology #primarycare
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