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diagnosis differential leukemia algorithm aplastic causes chronic comparison hodgkins larva lymphocytic lymphoma management mds migrans monoclonal myelodysplasia myelodysplastic nonhodgkins paraproteinemias
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
- infiltrates (anemia ... violaceous, nontender cutaneous ... -> Invade Skin: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
Skin Ulcers by Etiology ... Mycosis fungoides (cutaneous ... • Bleomycin Hematologic ... Anemia • Thalessemia ... #dermatology #Differential
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Hepatomegaly • Skin ... • Neutropenia, anemia ... diagnosis #workup #oncology ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Autoimmune diseases • Clinical ... Hepatosplenomegaly, cytopenias(bleeding ... disease: GI, neuro, cutaneous ... NonHodgkins #comparison #oncology ... #differential #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... Clinical Presentation ... Headaches • Pale skin ... ecchymoses, mucosal bleeding ... #oncology #hematology
Cutaneous larva migrans skin Rash 25 F recent Caribbean vacation, walked barefoot on sand and now with
migrans skin Rash ... CLM most commonly ... Diagnosis is clinical ... larva #migrans #skinRash ... #dermatology #clinical
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... gangrenosum • Cutaneous ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... just beneath the skin ... are caused by bleeding ... Syndromes #diagnosis #hematology ... #oncology
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