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diagnosis management oncology causes product reactions activation anemia antimda5 antimda5dm aplastic coagulation dermatologic dermatomyositis dic differential disorders disseminated gpa granulomatosis
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Maculopapular rash ... vasculitis (inflamed blood ... Polyangiitis #GPA #dermatology ... #rash #diagnosis ... #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- History of bleeding ... (petechiae, ecchymoses ... epistaxis, gingival bleeding ... plateletcount), peripheral blood ... Causes #Workup #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
purpura to mucosal bleeding ... (Petechial or purpuric ... rash) • Heart, ... Diagnosis #Management #Hematology ... #Rheumatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Findings: • Bleeding ... ABO incompatible blood ... Findings: • Bleeding ... Manifestations of DIC: • Petechiae ... treatment #management #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... Blast cells - Blood ... blast cells - Blood ... Significant ↓ PLT: Petechiae ... #Leukemia #Hematology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
(blue-purple) rash ... • Erythematous rash ... onset [33-74%] • Blood ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
work properly, leading ... unusual bruising or bleeding ... are caused by bleeding ... (petechiae) • ... Syndromes #diagnosis #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... , and petechiae ... result from low blood ... Anemia #oncology #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
recipient antibodies leading ... maculopapular rash ... Injury (TRALI): Leading ... coagulopathy & ↑bleeding ... diagnosis #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... maculopapular rash ... Injury (TRALI): Leading ... coagulopathy & ↑bleeding ... diagnosis #management #hematology
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