19 results
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
erythroderma, petechiae ... Ill-appearing, vital sign ... New-onset fever with rash ... #Diagnosis #Dermatology ... #Rash #Maculopapular
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Maculopapular rash ... • Goodpasture syndrome ... vasculitis (inflamed blood ... Polyangiitis #GPA #dermatology ... #rash #diagnosis
Erythematous Rashes - THE ALGORITHMIC APPROACH

Characterized by diffuse redness of the skin due to
capillary congestion, erythematous
and toxic shock syndrome ... erythematous rash ... may be having ... #Diagnosis #Dermatology ... #Erythematous #Rash
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
purpura to mucosal bleeding ... (Petechial or purpuric ... rash) • Heart, ... Diagnosis #Management #Hematology ... #Rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- History of bleeding ... (petechiae, ecchymoses ... epistaxis, gingival bleeding ... plateletcount), peripheral blood ... Causes #Workup #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
work properly, leading ... unusual bruising or bleeding ... are caused by bleeding ... (petechiae) • ... #diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
ALL: mediastinal mass ... Significant ↓ PLT: Petechiae ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... ecchymoses, mucosal bleeding ... , and petechiae ... result from low blood ... Anemia #oncology #hematology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
sudden onset of a rash ... - Rash: multiple ... Episcleritis Signs ... neutrophils in the blood ... #diagnosis #dermatology
Pigmented Purpuric Dermatoses (PPD) - Capillaritis

Group of chronic, benign, cutaneous eruptions characterized by the presence of
the presence of petechiae ... Extravasation of blood ... which allow red blood ... brown tint of the rash ... differential #diagnosis #dermatology