10 results
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Maculopapular rash ... • Goodpasture syndrome ... vasculitis (inflamed blood ... Polyangiitis #GPA #dermatology ... #rash #diagnosis
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
(MDS) What? ... unusual bruising or bleeding ... are caused by bleeding ... (petechiae) • ... #diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- History of bleeding ... (petechiae, ecchymoses ... Infection exposure (l MD ... plateletcount), peripheral blood ... Causes #Workup #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
ecchymoses, mucosal bleeding ... , and petechiae ... (MDS) (normal or ... result from low blood ... Anemia #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... Significant ↓ PLT: Petechiae ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
purpura to mucosal bleeding ... (Petechial or purpuric ... rash) • Heart, ... Diagnosis #Management #Hematology ... #Rheumatology
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Episcleritis Signs ... , breast CA - Hematologic ... neutrophils in the blood ... #diagnosis #dermatology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Blood Transfusion ... maculopapular rash ... coagulopathy & ↑bleeding ... infographic by Nick Mark MD ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
maculopapular rash ... Injury (TRALI): Leading ... coagulopathy & ↑bleeding ... by Nick Mark MD ... diagnosis #management #hematology
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... From Blood Cancer ... Myelodysplastic syndromes ... an infection or bleeding ... #algorithm #hematology