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diagnosis differential leukemia management rheumatology workup activation algorithm aplastic atlas cancer causes chronic dermatologic disorders gpa granulomatosis key lymphocytic macrophage
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Significant ↓ PLT: Petechiae ... - infiltrates (anemia ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... Myelodysplastic syndrome ... Liver diseases, Bleeding ... Hemolytic uremic syndrome ... #differential #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
cell count (anemia ... are caused by bleeding ... (petechiae) • ... #diagnosis #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... diagnosis #workup #oncology ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... ecchymoses, mucosal bleeding ... , and petechiae ... result from low blood ... #oncology #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Maculopapular rash ... • Goodpasture syndrome ... vasculitis (inflamed blood ... Polyangiitis #GPA #dermatology ... #rash #diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
(petechiae, ecchymoses ... plateletcount), peripheral blood ... changes), high MCV anemia ... not required in all ... Causes #Workup #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
purpura to mucosal bleeding ... (Petechial or purpuric ... rash) • Heart, ... with leukopenia, anemia ... Diagnosis #Management #Hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Episcleritis Signs ... neutrophils in the blood ... #diagnosis #dermatology ... #oncology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... From Blood Cancer ... disease tolerate anemia ... an infection or bleeding ... #algorithm #hematology
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