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diagnosis oncology rheumatology differential management vasculitis activation anemia aplastic classification dermatologic gpa granulomatosis leukemia macrophage mas mds myelodysplasia myelodysplastic sweet
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Maculopapular rash ... • Goodpasture syndrome ... vasculitis (inflamed blood ... #GPA #dermatology ... #rash #diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
purpura to mucosal bleeding ... (Petechial or purpuric ... rash) • Heart, ... Diagnosis #Management #Hematology ... #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
the peripheral blood ... Significant ↓ PLT: Petechiae ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
work properly, leading ... unusual bruising or bleeding ... are caused by bleeding ... (petechiae) • ... #diagnosis #hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
- Rash: multiple ... Episcleritis Signs ... , breast CA - Hematologic ... neutrophils in the blood ... #diagnosis #dermatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... ecchymoses, mucosal bleeding ... , and petechiae ... result from low blood ... Anemia #oncology #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
• Microscopic Polyangiitis ... mucositis - Rash ... purpura: strong sign ... pulses, bruis, or blood ... Large Vessel: Blood
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... pulses, bruits, or blood ... , mucositis • Rash ... : Microscopic polyangiitis ... vasculitis • Cogan syndrome
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