6 results
diagnosis anemia blood product reactions activation leukostasis lysis macrophage mas oncology rheumatology tls transfusion treatment tumor
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... neutropenia • Mucosal bleeding ... Supportive care (transfusions ... Anemia #diagnosis #management ... #treatment #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... ecchymoses, mucosal bleeding ... Constitutional Syndromes ... Anemia #oncology #hematology ... #diagnosis #management
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
maculopapular rash ... due to marrow aplasia ... coagulopathy & ↑bleeding ... #diagnosis #management ... #hematology #reactions
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... due to marrow aplasia ... coagulopathy & ↑bleeding ... #diagnosis #management ... #hematology #reactions
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... Diuretics, PRBC transfusion ... WBC >100k, + lab signs ... TLS #diagnosis #management ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
IL-1 and IL-6, leading ... purpura to mucosal bleeding ... Petechial or purpuric rash ... #Diagnosis #Management ... #Hematology #Rheumatology
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