9 results
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
common inherited bleeding ... bruising • Skin ... bleeding from mucosal ... factor VIII) Treatment ... Disease #Diagnosis #Hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
purpura to mucosal bleeding ... Petechial or purpuric rash ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Headaches • Pale skin ... ecchymoses, mucosal bleeding ... aplastic anemia Treatment ... Anemia #oncology #hematology
Helpful Clinical Features in Evaluating Bleeding Disorders
Age of onset
 • Neonate - in 20% of haemophilias,
in Evaluating Bleeding ... haemophilias, bleeding ... and skin haemorrhage ... History #peds #pediatrics ... #diagnosis #hematology
Monkeypox

What?
Monkeypox virus belongs to the family Poxviridae, subfamily Chordopoxvirinae, and genus orthopoxvirus
Viral zoonotic disease that is
Characteristic Rash ... Umbilification - Rash ... rectal pain, rectal bleeding ... Respiratory distress Treatment ... Diagnosis #Management #Dermatology
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
maculopapular rash ... Injury (TRALI): Leading ... coagulopathy & ↑bleeding ... infections with skin ... diagnosis #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
maculopapular rash ... Injury (TRALI): Leading ... coagulopathy & ↑bleeding ... infections with skin ... diagnosis #management #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... just beneath the skin ... are caused by bleeding ... factor (GCSF) treatments ... Syndromes #diagnosis #hematology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
(blue-purple) rash ... • Erythematous rash ... positive patients Treatment ... diagnosis #management #rheumatology ... #dermatology