13 results
Venous Thromboembolism Treatment Algorithm
Branch points: 
Active bleeding?  Active malignancy? Provoked?

- Dr. Joseph Shatzel
@Clotmaster

#Management #VTE #DVT
Thromboembolism Treatment ... points: Active bleeding ... #Management #VTE ... Thromboembolism #Treatment ... #Hematology #Anticoagulation
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
for VTE in Malignancy ... thrombosis in cancer ... #Anticoagulation ... #Management #Hematology ... #Oncology
Bleeding risk calculators - HAS-BLED (atrial fibrillation) and IMPROVE (VTE prophylaxis for inpatients)
Important notes:
 • No
) and IMPROVE (VTE ... validated for VTE ... treatment, only ... of withholding anticoagulation ... #Factors #Hematology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... body mass index; VTE ... #Anticoagulation ... #Management #Hematology ... #Oncology
Longterm Venous Thromboembolism Treatment Algorithm
Treat for 3 months and reassess
 • Isolated distal DVT (without cancer)
Thromboembolism Treatment ... PE - High Bleeding ... therapy - Second VTE ... Algorithm #management #hematology ... #anticoagulation
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... DOACs thereby leading ... metabolization leading ... #Chemotherapy #Oncology ... #Hematology #Interactions
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... ecchymoses, mucosal bleeding ... Treatment: ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
- infiltrates (anemia ... • Significant bleeding ... lymphoid organs When Cancer ... #Leukemia #Hematology ... #Oncology #Diagnosis
Clotmaster Consensus 2019: Duration of Therapy for Venous Thromboembolic Disease
 • Superficial Venous Thrombosis
 • Upper
Thrombophilia • Cancer ... DeLoughery @Bloodman #VTE ... #anticoagulation ... management #DVT #hematology ... #length #treatment
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... • Neutropenia, anemia ... microglobulin Treatment ... diagnosis #workup #oncology ... #hematology