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anticoagulation management pharmacology oncology algorithm cancer malignancy noac aptt bridging chemotherapy cyp3a4 dabigatran dosing dvt inducers inhibitors interactions laboratory loading
Oral anticoagulant dosing and bridging for VTE - Dr. Joseph Shatzel @Clotmaster #VTE #DOAC #Bridging #Dosing #Oral
Oral anticoagulant ... #DOAC #Bridging ... #Dabigatran #Apixaban ... #Rivaroxaban #Edoxaban ... #Pharmacology #Hematology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis. Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... Currently, edoxaban ... anticoagulants ... #DOAC #VTE #Malignancy ... Anticoagulation #Management #Hematology
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 DOAC Reversal Emergency surgery or urgent procedure Stop anticoagulant treatment; volume resuscitation and transfusion as needed Antidotes: • Apixaban,
treatment; volume ... Antidotes: • Apixaban ... , Edoxaban or Rivaroxaban ... #Oral #anticoagulant ... #hematology #management
Treatment algorithm for VTE in Malignancy (A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
for VTE in Malignancy ... **Edoxaban is initiated ... DOAC, direct oral ... #DOAC #VTE #Malignancy ... Anticoagulation #Management #Hematology
Perioperative Management of DOACs Problem: ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
direct acting oral ... anticoagulants ... and procedural bleeding ... inhibitor) • Apixaban ... , Edoxaban, Rivaroxaban
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
) Cancer-treatment ... Edoxaban, rivaroxaban ... , and apixaban are ... Rivaroxaban and apixaban ... Chemotherapy #Oncology #Hematology
Effect of Direct Oral Anticoagulants on Hemostatic Tests Horizontal bars correspond to the approximate range of detectability
Effect of Direct Oral ... Anticoagulants ... , rixaroxaban, apixaban ... and edoxaban. ... #hematology #laboratory
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