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diagnosis aplastic blood differential oncology product reactions activation b12 folate folicacid macrophage mas myelodysplasia myelodysplastic rheumatology syndrome syndromes transfusion transfusions
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Aplastic Anemia ... neutropenia • Mucosal bleeding ... Can progress to MDS ... #diagnosis #management ... #treatment #hematology
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
Etiologies of Folate Deficiency ... have hemolytic anemia ... interfered with leading ... differential #diagnosis #hematology ... #nutrition
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... , GATA2 deficiency ... , CTLA4 deficiency ... #oncology #hematology ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
unusual bruising or bleeding ... are caused by bleeding ... Platelet Disorders • Nutritional ... or folic acid deficiency ... Syndromes #diagnosis #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
IL-1 and IL-6, leading ... purpura to mucosal bleeding ... with leukopenia, anemia ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Etiologies of Vitamin B12 Deficiency • Inadequate intake - Rare but seen in very strict vegans
of Vitamin B12 Deficiency ... pump blockers is leading ... autoantibodies (pernicious anemia ... differential #diagnosis #hematology ... #nutrition
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
recipients w/ IgA deficiency ... coagulopathy & ↑bleeding ... infographic by Nick Mark MD ... Transfusion #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
recipients w/ IgA deficiency ... coagulopathy & ↑bleeding ... by Nick Mark MD ... Transfusions #diagnosis #management ... #hematology #reactions
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