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differential rheumatology approach arthritis causes pathophysiology physicalexam workup agglutinin algorithm anemia classification cold comparison conditions degenerative dermatology disease effusions extrarticular
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... tumor • Non-bloody ... - parvovirus, HIV ... #Joint #Pain #MSK ... #rheumatology #
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
after > 1 hr • Blood ... commonly affects the knee ... hip and L/C-spine ... Comparison #Versus #MSK ... JointDisease #JointPain #Diagnosis
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
- Differential Diagnosis ... Fever/Chills/Joint ... pain/Night sweats ... - DDX: - Infection ... #msk #physicalexam
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
present both at rest ... Acute or chronic infections ... e.g., congenital hip ... #Pain #MSK #rheumatology ... #differential #diagnosis
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings - Infectious Agents - 50% have
endothelial lining of blood ... Colicky abdominal pain ... , vomiting, GI bleeding ... insufficiency - Joints ... Pathophysiology #Diagnosis
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Differential Diagnosis ... - Vasculitis ... lesions • Severe pain ... ITP - APLS - HIT ... test • Serology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
vesicular eruption - Joints ... pulses, bruis, or blood ... Large Vessel: Blood ... retinopathy Lab Tests ... #rheumatology #
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pain Eyes ... Lyme disease, Vasculitis ... arteritis • Bloody ... nodes (PIP joints ... #diagnosis #rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... sensitize red blood ... chills, flank pain ... test #cold # ... hemolytic #anemia #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
pulses, bruits, or blood ... of shoulder and hip ... tract: Abdominal pain ... Palpable purpura, joint ... #Rheumatology
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