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differential hepatology algorithm hepatitis lfts management rheumatology abnormal activation amyloidosis cancer chemistry comparison enzymes hellp icp infections infectiousdiseases injury interpretation
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
as neoplasm or amyloid ... disease: > 2 ... RBC (hemolysis, bleeding ... • Gilbert's syndrome ... #chemistry #diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... vein: Budd-chiari syndrome ... • Gilbert's syndrome ... RBC (hemolysis, bleeding ... #differential #diagnosis
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... necrosis HELLP Syndrome ... of Pregnancy (AFLP ... #differential #diagnosis ... #icp #HELLP #AFLP
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
presence of metabolic syndrome ... ALP, alkaline phosphatase ... disease; AST, aspartate ... disease; T2DM, ... mellitus; USS, ultrasound
Amyloidosis - Summary Group of disorders associated with extracellular deposition of fibrils formed from low-molecular-weight proteins in
Clinical suspicion ... the extent of disease ... : • Nephrotic syndrome ... failure • GI bleeding ... imaging of liver
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... Fever is the main clinical ... thrombocytopenia • Liver ... #Diagnosis #Management ... #Hematology #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... salivary ducts Clinical ... vasculitis: 10%-16% Liver ... Nephrogenic DI Hematologic ... phenomenon (16%) MSK
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Lady Windermere Syndrome ... : • Syndrome of ... Hematologic malignancy ... (elevations of liver ... • Clinical (Symptoms
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... median age at diagnosis ... an infection or bleeding ... importance of clinical ... #algorithm #hematology
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