10 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... Idiosyncratic #differential ... gastroenterology #algorithm ... gastroenterology #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... RBC (hemolysis, bleeding ... • Gilbert's syndrome ... chemistry #diagnosis #differential ... #LFTs #RValue #
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
tests algorithm ... presence of metabolic syndrome ... #LFTs #Abnormal ... #Algorithm #Hepatology ... #Differential #
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... vein: Budd-chiari syndrome ... RBC (hemolysis, bleeding ... #hepatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Clinical Presentation ... purpura to mucosal bleeding ... thrombocytopenia • Liver ... #Diagnosis #Management ... #Hematology #Rheumatology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
renal failure Clinical ... nodules; anterior/posterior ... MSK, heart (2-5% ... ), liver (pain/abnormal ... LFT): 12-20%, spleen
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
stores in the liver ... beta-oxidation in the liver ... for Refeeding Syndrome ... #diagnosis #differential ... #algorithm #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
salivary ducts Clinical ... vasculitis: 10%-16% Liver ... Nephrogenic DI Hematologic ... phenomenon (16%) MSK ... Diagnosis #Management
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
just simply a clinical ... causing hypovolemia needing ... acute coronary syndrome ... #diagnosis #differential ... #algorithm #management
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Lady Windermere Syndrome ... : • Syndrome of ... Hematologic malignancy ... (elevations of liver ... NTM #Infections #differential