18 results
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
) Cancer-treatment ... thereby leading ... metabolization leading ... #Chemotherapy #Oncology ... #Hematology #Interactions
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
at high risk of bleeding ... DOAC, direct oral ... #DOAC #VTE #Malignancy ... Anticoagulation #Management #Hematology ... #Oncology
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... anticoagulants (DOACs ... filtration rate; DOAC ... Anticoagulation #Management #Hematology ... #Oncology
Perioperative Management of DOACs
Problem:
 ✖ Each year approximately 250,000 patients on chronic anticoagulation in North America
250,000 patients on chronic ... interruption per treatment ... and procedural bleeding ... with a very low bleeding ... Perioperative #Management #Treatment
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
Leukemia - History of Bleeding ... Age > 50 • Chronic ... Algorithm #Causes #Hematology ... #Oncology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... months without treatment ... #ACLF #Acute #Chronic ... Failure #Cirrhosis #Hepatology ... #gastroenterology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Classify severity Treatment ... Chronic Management ... by a hemophilia treatment ... Diagnosis #Management #treatment ... #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... with a relatively chronic ... involvement CML (Chronic ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... transformation) Treatment ... uw_IMresidency #CLL #Chronic ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Systemic Therapy for Hepatocellular Carcinoma - AGA Clinical Practice Guideline

First Line Treatment for HCC with Preserved
First Line Treatment ... Function Second Line Treatment ... #Management #Hepatology ... #Gastroenterology ... #oncology #Pharmacology