288 results
Selected Clinical Trials of SGLT2 inhibitors in CVD and CKD
EMPA-REG OUTCOME - Empagliflozin lowered CV events
and CKD EMPA-REG ... SGLT2i in HF and CKD ... outcomes in HFrEF on GDMT ... outcomes in HFrEF on GDMT ... #CKD
Guidelines Directed medical therapy for Heart Failure 

Satyendra Dhar, MD, @DharSaty

#HFrEF #GDMT #sodium-glucosecotransporter-2inhibitors #SGLT2i #reninangiotensinaldosteronesysteminhibitors
DharSaty #HFrEF #GDMT ... EMPEROR-Reduced #Carvedilol
Definitions of AKI, CKD, AKD
Acute Kidney Injury (AKI):
 • Increase in SCr by 2 50% within
Definitions of AKI, CKD ... , AKD Acute Kidney ... Kidney Disease (CKD ... /CKD • No structural ... damage #AKI #CKD
HFrEF: Guideline Directed Medical Therapy

"Must Be On"
 • ACEI, ARB, or ARNI AND select Beta Blockers
Blockers (bisoprolol, carvedilol ... chf #cardiology #GDMT
Beta blocker Conversion Table- Carvedilol, Metoprolol and Bisoprolol Equivalents
Converting between Beta-Blockers: Carvedilol, Metoprolol and Bisoprolol

#Pharmacology #Cardiology
Conversion Table- Carvedilol ... Beta-Blockers: Carvedilol ... Table #Metoprolol #Carvedilol
Metoprolol and Carvedilol - Immediate to Extended Release Dose Conversions

Metoprolol 
Immediate (tartrate) -> Extended (succinate) 
25
Metoprolol and Carvedilol ... 200 mg daily Carvedilol ... #Metoprolol #Carvedilol
Guideline-Directed Medical Therapy (GDMT) in HFrEF and CKD

 • Class I pillars of HFrEF GDMT across
Medical Therapy (GDMT ... ) in HFrEF and CKD ... pillars of HFrEF GDMT ... after core GDMT ... #CKD #HFrEF #management
Stages in the development of HF and recommended therapy by stage. ACEI indicates angiotensin-converting enzyme inhibitor;
angiotensin-receptor blocker; CAD ... ejection fraction; GDMT
Oral Antihypertensive Medications - Selection by Comorbidities
Comorbidities: 
 • Stable Angina, HFpEF, HFrEF, AFib, TAA/Marfan, Aortic
Dissection • CKD ... , DM, ESRD, PKD
Heart Failure (HFrEF) Treatment - GDMT for stage C 

For patients with Heart Failure with REDUCED
HFrEF) Treatment - GDMT ... Medical Therapy (GDMT ... GDMT is basically