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oncology als apml behcet chronic classification differentiation encephalopathy fungal hemophagocytic hlh hodgkins infections infectiousdiseases lateral leukemia lymphocytic lymphohistiocytosis lymphoma mycoses
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... ’s lymphoma or acute ... #workup #oncology ... #hematology
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Pathophysiology ... fasciculations Common Symptoms ... Treatment: - Multidisciplinary ... #neurology #diagnosis ... #management
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Pathophysiology ... : >3 symptoms, or ... initiation • Differential ... #management #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: HLH signs and ... symptoms can mimic ... presents as an acute ... #management #treatment ... #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... ) Differential Diagnosis ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
Shock, Autoimmune disease ... Etiology: • Pathophysiology ... Neurological symptoms ... Reversible course Differential ... #diagnosis #management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... , particularly scleritis ... purpura: Strong sign ... • Progressive symptoms ... #Diagnosis #Rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
ingestion • B symptoms ... Hodgkin Lymphoma Workup ... number of sites of disease ... classification #hematology ... #oncology #management
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
presents with acute ... • Rheumatologic ... • Sclerosing mediastinitis ... Aspergillosis Pathophysiology ... #Management #Infections
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