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vasculitis apml differentiation erythematosus fungal hodgkins infectiousdiseases leukemia lupus lymphocytic lymphoma mds mycoses myelodysplasia myelodysplastic sle syndromes systemic vasculitides
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... weeks without infection ... Physical Exam/Signs ... #workup #oncology ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Pathophysiology ... : >3 symptoms, or ... Diagnosis: Infection ... #management #hematology ... #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... fibromyalgia) • Infections ... Induced Lupus: • Symptoms ... with Lupus: • Chronic ... #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Marrow Failure • Chronic ... Myeloproliferative Disease ... #diagnosis #hematology ... #oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... , particularly scleritis ... purpura: strong sign ... #diagnosis #rheumatology ... #classification
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... ingestion • B symptoms ... Hodgkin Lymphoma Workup ... #hematology #oncology ... #management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
, particularly scleritis ... purpura: Strong sign ... • Progressive symptoms ... Eosinophilia, asthma, chronic ... #Diagnosis #Rheumatology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
• Rheumatologic ... • Sclerosing mediastinitis ... Aspergillosis Pathophysiology ... : • Acute or chronic ... #Management #Infections
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