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management oncology disease vasculitis agglutinin apml arteritis behcet chronic cll cold differentiation erythematosus gca giantcell gout hemolytic hodgkins leukemia lupus
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... anemia • Cold ... younger pts) Differential ... chills, flank pain ... #hematology #diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Pathophysiology ... : >3 symptoms, or ... initiation • Differential ... #management #hematology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
skin injury) • Neurologic ... Arthritis, AS Treatment ... Nonsurgical abdominal pain ... #signs #symptoms ... #rheumatology #
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... • Neutropenia, anemia ... microglobulin Treatment ... workup #oncology #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... permanent alopecia Differential ... Arthritis: • Joint pain ... Induced Lupus: • Symptoms ... #Rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... very remarkable w/differential ... systemic complaints- anemia ... them, but urgent rheumatology ... #Symptoms #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Diagnosis Framework ... Presentation - Systemic Symptoms ... purpura: strong sign ... #diagnosis #rheumatology ... #classification
Gout - Diagnosis and Management Summary 3 Conditions for Gout to Manifest: 1. Hyperuricemia 2. Monosodium urate deposition in
sex • Metabolic syndrome ... swelling, significant pain ... not possible • Ultrasound ... double contour sign ... #rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Pain in LN ... ingestion • B symptoms ... Immunohistochemical studies (to differentiate ... Hodgkin Lymphoma Treatment ... #hematology #oncology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Presentation: Systemic Symptoms ... purpura: Strong sign ... affects the skin, neurologic ... • Progressive symptoms ... #Diagnosis #Rheumatology
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