7 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinins (CAD ... (CAD): - Idiopathic ... testing for anti-C3d ... agglutination After CAD ... #hematology #diagnosis
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... Splenomegaly - CTD ... EGPA - MPA • CTD ... #Diagnosis #hematology
Primary and Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Primary (Essential) (95%) - Onset between age
Hypertension - Differential ... Diagnosis Algorithm ... taken at home, work ... - CKD, AKI, Glomerulonephritis ... #HTN #Cardiology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... Diagnosis and Workup ... (CVID, WAS), (neurologic ... ITP, unexplained pancytopenia ... #hematology
Secondary Causes of Hypertension - Differential Diagnosis Algorithm
Hypertension - BP > 140/90 (>130/80 for DM)
Hypertensive urgency
Diagnosis Algorithm ... HTN • Onset < ... Renal Parenchymal Diseases ... syndrome • AKI/CKD ... #Secondary #Nephrology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Causes of Secondary ... Renal parenchymal disease ... : CKD, acute glomerulonephritis ... most pts have HTN ... Neurologic disorders
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
et diutinum Neurologic ... thrombosis+Pulm HTN ... Autoantibodies: • WAIHA • CAD ... • Coombs (-) hemolytic ... #Monoclonal #Differential