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hemolytic systemic generalized pruritus approach extravascular hemolysis hodgkins intravascular lymphoma mds myelodysplasia myelodysplastic naildisorders nonpalpable palpable petechiae petechial physicalexam platelet
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Disease (CAD): ... Secondary Cold ... anemia • Cold ... #agglutinin #disease ... #hematology #diagnosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... - Hemolytic anemia ... Diagnosis #hematology ... #nonpalpable #dermatology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Diagnosis Algorithm ... • Rheumatic disorders ... • Celiac disease ... #Diagnosis #Algorithm ... #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
thrombocytopenic purpura ... agglutin disease ... lymphoproliferative disorders ... #differential # ... diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... Agglutination - Cold ... agglutinins disease ... Diagnosis #Algorithm ... #workup #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... Diagnosis and Workup ... changes), high MCV anemia ... Diagnosis #Causes ... #Workup #hematology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... Nail Fold Abnormality ... #dermatology #Differential ... #Diagnosis #Algorithm ... #causes
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Diagnosis Algorithm ... Disease • Marrow ... #Classification ... #Diagnosis #Algorithm ... #Causes #Hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Diagnosis Algorithm ... Pruritus #primary #secondary ... #generalized #dermatology ... Diagnosis #Algorithm ... #causes
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Diagnosis Algorithm ... #Pruritus #secondary ... #generalized #dermatology ... Diagnosis #Algorithm ... #causes
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