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pruritus common cvid erythematosus gap globulin hypogammaglobulinemia immunodeficiency immunology lupus lymphocytic mds myelodysplasia myelodysplastic naildisorders primary protein proteingap rheumatology sle
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis ... Algorithm - Systemic ... #systemic #generalized ... #dermatology #Differential ... #Diagnosis #Algorithm
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Diagnosis Algorithm ... #systemic #generalized ... #dermatology #Differential ... #Diagnosis #Algorithm ... #causes
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... • Neutropenia, anemia ... #CLL #Chronic ... #diagnosis #workup ... #oncology #hematology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... to Systemic Diseases ... #Secondary #dermatology ... Diagnosis #Algorithm ... #causes
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... extramedullary disease ... -> Invade Skin: ... #Hematology #Oncology ... #Diagnosis
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
disease. ... Rare Disorder: ... Causes: - Idiopathic ... #diagnosis #dermatology ... #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Frank nephritis (hypertension ... lymphopenia, low PLT • Anemia ... with Lupus: • Chronic ... Hodgkin lymphoma and leukemia
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... Causes • Anemia ... Cell Leukemia ... #diagnosis #hematology ... #oncology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... infection risk secondary ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... gammopathy, and skin ... gastric tumors • Hematology ... anemia • Other ... #diagnosis #hematology
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