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systemic hemolytic pruritus agglutinin cold diffuse focal hairloss hemolysis intravascular mds myelodysplasia myelodysplastic naildisorders nonpalpable palpable platelets primary purpura rheumatology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... Diagnosis Secondary ... Myelodysplastic syndrome ... Diagnosis #Causes ... #hematology #secondary
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... #Causes #differential ... #diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... → Refer to hematology ... Kawasaki, Nephrotic syndrome ... #Diagnosis #Algorithm ... #hematology
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
Diagnosis Algorithm ... • Loose anagen syndrome ... #dermatology #Differential ... #Diagnosis #Algorithm ... #causes
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic anemia ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... #Diagnosis #hematology ... #nonpalpable #dermatology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #dermatology #Differential ... #Diagnosis #Algorithm
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... • Nephrotic syndrome ... #dermatology #Differential ... #Diagnosis #Algorithm ... #causes
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
AIHA Primary Secondary ... Secondary Cold ... Agglutinin Syndrome ... younger pts) Differential ... #hematology #diagnosis
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Diagnosis Algorithm ... Myelodisplastic syndrome ... #dermatology #Differential ... #Diagnosis #Algorithm ... #causes
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... Causes • Anemia ... Myeloproliferative Disease ... #diagnosis #hematology ... #oncology
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