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anemia hemolytic bandemia causes chronic classification cold diffuse erythematosus lad leukemia lupus lymphadenopathy lymphocytic management monoclonal neutrophil paraproteinemias plasmacytoma rheumatology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Diagnosis Algorithm ... (Pancytopenia, WBC ... Lymphocytic Leukemia (CBC ... #Diagnosis #Algorithm ... #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
lymphoma SLL ... Lymphocytosis on CBC ... can indicate disease ... #workup #oncology ... #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
malignancy (CLL ... Blood smear - RBC ... malignancies -> CLL ... significance (MGUS), CLL ... #anemia #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... Consider sickle cell ... • Unusual RBC ... #Diagnosis #Algorithm ... #workup #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Workup: • Full ... platelets - WBC ... #lymphoma #diagnosis ... classification #hematology ... #oncology #management
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
Left Shift: • Cell ... precursors" • Stab cell ... Even with normal WBC ... 21% had normal WBC ... #WBC #CBC #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
(HCV) • CLL & ... +Organomegaly+↑RBC ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Angioimmunoblastic T-cell ... Frank nephritis (hypertension ... titers > 1:80 • CBC ... : • Chronic B-cell
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
• Plasma cell neoplasms ... MM, the plasma cell ... • CBC + diff • ... #Diagnosis #Workup ... #Hematology
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