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causes pruritus agglutinin chronic classification cll cold cvid hemolytic hodgkins hypogammaglobulinemia immunodeficiency immunology leukemia lymphocytic lymphoma mcv mds monoclonal myelodysplasia
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... to Anemia - Differential ... , CKD • Hemolytic ... Non-megaloblastic: Liver disease ... Diagnosis #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... → Refer to hematology ... , Celiac disease ... #Diagnosis #Algorithm ... #hematology
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Differential Diagnosis ... Algorithm - Systemic ... #systemic #generalized ... #dermatology #Differential ... #Diagnosis #Algorithm
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinins (CAD ... (CAD): - Idiopathic ... Diagnosis: • hemolytic ... #hemolytic #anemia ... #hematology #diagnosis
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- CTD (SLE) ... EGPA - MPA • CTD ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Diagnosis Algorithm ... #Pruritus #secondary ... #systemic #generalized ... #dermatology #Differential ... #Diagnosis #Algorithm
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... and autoimmune hemolytic ... anemia) • Systemic ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Autoantibodies: • WAIHA • CAD ... • Coombs (-) hemolytic ... anemia due to cold ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Diagnosis Algorithm ... Better call hematology ... , think about common ... #Diagnosis #Algorithm ... #workup #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Epidemiology: • Most common ... cells can indicate disease ... • Neutropenia, anemia ... #workup #oncology ... #hematology
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