12 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
mutated in one cell ... Retinoblastoma Signs ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs
Gynecomastia - Differential Diagnosis Algorithm
No Testicular Mass on Ultrasound
 • Adrenal Neoplasm
 • Increased Extraglomerular Aromatase
Differential Diagnosis Algorithm ... Testicular Mass on Ultrasound ... Testicular Mass on Ultrasound ... Differential #Diagnosis #Algorithm ... #causes #endocrinology
Bell's Phenomenon on Physical Exam

Carles Bell realized that when trying to close the eye on the
neurologiabr #Bells ... #Phenomenon #Sign ... #PhysicalExam #ophthalmology ... #neurology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
pathway -> Incr cell ... activates lipolysis Signs ... #FeedbackLoop #endocrinology ... #pathophysiology
Hypochloremia - Differential Diagnosis Algorithm

Cause - Decreased Intake:
 • Low salt in diet
 • Exclusive D5W
Differential Diagnosis Algorithm ... - Gitelman SIGNS ... smooth muscle cells ... #Pathophysiology ... #Nephrology #Chloride
Central Retinal Artery Occlusion: Pathogenesis and clinical findings
 • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
-> Endothelial cell ... lymphoma, sickle cell ... Occlusion #CRAO #pathophysiology ... #ophthalmology ... #diagnosis #signs
Xeropthalmia: Pathogenesis and Ocular Manifestations

Decr Visual pigment -> Keratinization, thickening & non-wetting of the conjunctiva
conjunctiva -> Goblet cell ... #Xeropthalmia #pathophysiology ... #ophthalmology ... #diagnosis #signs
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA)

1) Is visual loss caused
Recognition of giant cell ... Doppler US : halo sign ... #Rheumatology #Ophthalmology ... #Diagnosis #Algorithm
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings
 • Note: in DKA, body K+ is lost
diffusion of K+ out of cells ... Signs/Symptoms/Complications ... DiabeticKetoacidosis #DKA #pathophysiology ... #endocrinology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Microglial cells ... are the immune cells ... between nerve cells ... Lateral #Sclerosis #neurology