11 results
Bone resorption and the relationship between osteoblasts and osteoclasts.  
RANK is expressed on the osteoclasts,
signals from other cell ... expressed on marrow cells ... Several acids (e.g ... #Pathophysiology ... #Endocrinology
A red blood cell (red arrow) is seen crossing the basement membrane (blue arrow) and losing
A red blood cell ... losing its shape, one ... pathology #clinical #pathophysiology ... #microscopy
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... Activation of CD8 T cells ... , Biological + Bone ... , Hb), Hepatic dysfunction ... /ml, ↑ LDH • Bone
Erectile Dysfunction: Pathogenesis

Erectile Dysfunction - Persistent or recurrent inability to achieve an erection sufficient to achieve
Erectile Dysfunction ... and rigidity Endocrinologic ... Erectile Dysfunction ... -> Endothelia cell ... #Pathophysiology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Incr IGF1 • Bone ... pathway -> Incr cell ... #FeedbackLoop #endocrinology ... #pathophysiology
Menstrual Cycle Physiology: Ovarian Cycle – Follicular Phase Explained
Early Follicular Phase (Days 0-5)
 • Granulosa cells
• Granulosa cells ... follicle (the one ... growth (this is one ... #OvarianCycle #pathophysiology ... FollicularPhase #endocrinology
Diabetic Foot: Pathogenesis and clinical findings
 • Polyol Pathway - Excess glucose enters Polyol pathway ->
accumulates in cells ... essential for cell ... increasing cytogenetic dysfunction ... - Infection of bone ... #DiabeticFoot #pathophysiology
Menstrual Cycle Physiology: Correlating the Ovarian and Uterine Cycles
Note: Some charts show different relative levels of
One follicle ... the endometrium adds ... new cell layers ... #OvarianCycle #pathophysiology ... #comparison #endocrinology
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Transplantation including bone ... marrow or stem cell ... Etiology: • Pathophysiology ... unclear, endothelial dysfunction ... elevated white blood cell
Heat Illnesses and Heat Stroke - Differential Diagnosis Framework

Heat Cramps:
 • Muscle pain or spasm -
Collapse: • Pathophysiology ... Decreased vasomotor tone ... significant CNS dysfunction ... CNS dysfunction ... cardiomyopathy, ARDS