13 results
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
is of B-cell lineage ... marrow • Mature B-cell ... involvement • T-cell ... Leukemia (CLL) ... form of large cell
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
/Mature B cell neoplasm ... disease • B cell ... AIHA • Pure red cell ... lymphoma • Hairy cell ... leukemia #CLL
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Leukemia (CLL) ... • Peripheral smear ... , smudge cells are ... Transformation to large cell ... uw_IMresidency #CLL
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
🔬Tumor cells are ... size lymphoid cells ... Prolymphocytes #Smear ... #Peripheral #Pathology ... #Microscopy #Clinical
T-LGL leukemia - T-CeIl Large Granular Lymphocytic Leukemia
Clinical
 - Persistent (>6mo) lymphocytosis (2-20k) with proven clonality
Lymphocytic Leukemia ... required for dx - T-cells ... mature cytotoxic T-cell ... chronic LPD of NK cells ... are NK cells (sCD3
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Plasma cell leukemia ... primary plasma cell ... leukemia Genevieve ... formation #Clinical #Smear ... #Hematology #Pathology
Sickle cell anemia and Howell Jolly bodies (nuclear remnants).

 - Dr. Abubaker Elshaikh
@ElshaikhMD

#SickleCell #HowellJolly #Body #Bodies
Sickle cell anemia ... #Body #Bodies #Pathology ... #Hematology #Smear ... #Clinical #Microscopy
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Reed-Sternberg (RS) Cells ... - 5% RS cells absent ... (LP) tumour B cells ... common - T Cell ... ~10% - B-Cell
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
low red blood cell ... low white blood cell ... hematopoiesis cell ... or three blood cell ... or more blood cell
Peripheral blood findings in microangiopathic hemolytic anemia.  DIC is a clinical and laboratory diagnosis, not
non-specific red cell ... polychromatophilic cells ... arrow) Peripheral smear ... anemia #Hematology #Pathology ... #Smear #Microscopy