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differential aids hematology management neurology oncology pulmonary rheumatology treatment 1 agglutinin anemia autoimmune brain cdi cdiff clinical clostridioides clostridium cold
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
CNS Infection in ... enhancement on CT ... Infections in HIV ... #CNS #Infections ... opportunistic #InfectiousDiseases
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
- Differential Diagnosis ... -> PNS -> NMJ - ... parainfluenza, Coxsackie, HIV ... cryoglobulins • PNS ... #Differential #Diagnosis
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
EGPA) • Renal: (AKI ... Other tests: • CT ... confirm DAH, r/o infection ... recent DAN) • EMG/NCS ... seen on chest CT
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
suspected) - CT ... (CRS) / ICANS: ... bispecifics, or HSCT - CRS ... 2–4 days after CRS ... Oncology #HemeOnc #Diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... develop leukostasis syndrome ... : CNS manifestations ... • Tumor lysis syndrome ... Hematology #Oncology #Diagnosis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... (CAS): - Due ... - Mycoplasma, EBV ... , HIV, rubella legionella ... disease (younger pts
Lung Infections in HIV - Differential Diagnosis Framework Disease by CD4 Count: Any CD4 Count: • Mycobacterium tuberculosis,
Lung Infections ... Diagnosis Framework ... • CT: Halo sign ... Lymphadenopathy, CNS ... #infectiousdiseases
C.diff - Clostridioides Difficile Infection (CDI) - Diagnosis and Management - GrepMed Handbook Clinical Presentation + Progression:
of hospitalized pts ... Acute Diarrhea (>3 BM ... equivocal • CT ... Bezlotoxumab 10 mg/kg IV ... #treatment #infectiousdiseases
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... Vasculitis Differential Diagnosis ... to exclude are infections ... pain and GN Anti-GBM ... chorioretinitis, CNS
Endocarditis - Overview and Differential Diagnosis Framework Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV
and Differential Diagnosis ... Infectious: • Pre-existing ... devices (CIED) Non-Infectious ... Cholesterol emboli syndrome ... #cardiology #infectiousdiseases
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