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management differential disease oncology syndrome agglutinin aids algorithm anemia autoimmune behcet blood classification cold disorders hemolytic hemophagocytic hiv hlh hodgkins
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
and Differential Diagnosis ... , Auer rod • Lymphoid ... Lymphadenopathy, CNS ... Proliferation • Lymphoid ... Blood #Disorders #hematology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
CNS Infection in ... HIV-Associated CNS ... Antimicrobial treatment ... enhancement on CT ... Lymphoma: • CD4
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Parotid swelling CNS ... nervous system (CNS ... • 8%-27% for CNS ... Hematologic: ... Sjogrens #Syndrome #Rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... Mediastinal mass) • CT ... physical exam, CT ... Treatment • Early ... #hematology #oncology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
→Activation of CD8 ... Hodgkin, T-cell lymphoma ... , B-cell lymphoma ... #management #treatment ... #summary #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
• Cytopenia -> BM ... involvement • 30%: CNS ... leukostasis syndrome: CNS ... #Leukemia #Hematology ... #Oncology #Diagnosis
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
Retroperitoneum and aorta ... concentration PET-CT ... conventional imaging (aorta ... • "Reactive lymphoid ... #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
basal ganglia, CNS ... meningitis), MCC CNS ... Arthritis, AS Treatment ... collaboration • CNS ... signs #symptoms #rheumatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome (CAS ... autoimmune disorder or lymphoid ... - Monoclonal - Lymphoid ... - Mycoplasma, EBV ... hemolytic #anemia #hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... < 30 years • Aorta ... Arteritis): • Aorta ... chorioretinitis, CNS ... #Rheumatology
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