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management differential classification disease symptoms syndrome arteritis behcet gca giantcell hemeonc hemophagocytic hlh hodgkins igg4 lymphohistiocytosis lymphoma myelitis neurology oncology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... glomerulonephritis) • Anti-GBM ... purpura: strong sign ... • ANA (Suggest CTD ... #rheumatology #
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
Retroperitoneum and aorta ... concentration PET-CT ... conventional imaging (aorta ... No necrosis, No vasculitis ... #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
, small-vessel vasculitis ... ) Differential Diagnosis ... Arthritis, AS Treatment ... #management #signs ... #symptoms #rheumatology
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
those coming off aorta ... systemic sx + signs ... = vasculitis vs ... Treatment of GCA ... them, but urgent rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis Framework ... purpura: Strong sign ... < 30 years • Aorta ... Arteritis): • Aorta ... #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
) • Cutaneous vasculitis ... Hematologic: ... : 2% Systemic Vasculitis ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• History of EBV ... Mediastinal mass) • CT ... physical exam, CT ... Hodgkin Lymphoma Treatment ... classification #hematology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... • Bilateral signs ... for brain and/or optic ... - Sjogren - Vasculitis ... Transverse Myelitis Treatment
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
Infections (e.g., EBV ... Presentation • Common Signs ... of NK cells and CD8 ... Treatment Approach ... #Management #Hematology
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