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diagnosis hematology differential management classification oncology algorithm blurry chronic cvid dermatologic disorders eosinophilia erythematosus gpa granulomatosis hypogammaglobulinemia immunodeficiency immunology leukemia
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... of about three cases ... supraclavicular node • Anterior ... (NSHL) - (most common ... classification #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... identical to the non-Hodgkin ... : • Most common ... Scoring system: ... workup #oncology #hematology
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Parasites Drugs: - DRESS ... Primary: - CML ... Lymphomas - Systemic ... Hypereosinophilic Syndrome ... #hematology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm Hodgkin ... site in lymphatic system ... with lymphatic system ... Depletion Non-Hodgkin ... pathophysiology #Hematology
Blurry Vision - Differential Diagnosis Framework Anatomical Approach to Eye Disease: 1. Lids/Lashes 2. Extraocular Muscles/Motility 3. Conjunctiva/Sclera 4. Cornea 5. Anterior
Anterior Chamber ... of Systemic Medications ... are much more common ... are much more common ... ophthalmology #causes
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
polyangiitis (GPA) is common ... disease or more commonly ... GPA causes disease ... • Goodpasture syndrome ... rash #diagnosis #rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... hemolytic anemia) • Systemic ... DDX - Other causes ... : • Nephrotic syndrome ... hypogammaglobulinemia #immunology #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
gland) biopsy • Ocular ... Hypocomplementemia • Can cause ... Central nervous system ... Malignancy Risk: • Non-Hodgkins ... #Rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Erythematous, macular ... Non-autoimmune rheumatologic ... Kidney disease common ... cyclophosphamide) • Hodgkin
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
CRP GCA (Giant Cell ... Nodosa: • PAN most commonly ... tract, and often causes ... : Ocular inflammatory ... Differential #Diagnosis #Rheumatology
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