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diagnosis management rheumatology allergy causes differential hematology hypersensitivity reactions table cell criticalcare cryoglobulinemia cryoglobulins erythematosus hemeonc hemophagocytic histiocytosis hlh hypertension
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
- Local and systemic ... cellular antigen, leading ... to complement activation ... Complement activation ... #Classification
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
cell antigens, leading ... to complement activation ... glomerulonephritis, Systemic ... allergy #table #classification ... #comparison
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... protein receptor type ... activin A receptor type ... heart disease Systolic ... dysfunction
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... , leading to the ... Syndrome: • Clinical ... disorder (e.g. systemic ... #classification
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... IL-1 and IL-6, leading ... fever syndromes Clinical ... Fever is the main clinical ... (CNS) dysfunction
Causes, classification and compensatory responses to shock. Shock can be caused by any pathological process that leads
Causes, classification ... vasodilatation, myocardial dysfunction ... shock is often clinically ... renin–angiotensin–aldosterone system ... Differential #Causes #Types
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Skin Disease Classification ... Kikuchi disease • Type-I ... mild cognitive dysfunction ... Chronic B-cell activation
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
cytopenias and organ dysfunction ... of the immune system ... Persistent fever, organ dysfunction ... Types of HLH • ... Clinical Presentation
Langerhans Cell Histiocytosis (LCH) Granulomatous Lesions comprising langerin-positive histiocytes and an inflammatory infiltrate can arise in virtually
virtually any organ system ... Langerhans cells, a type ... various tissues, leading ... populations) CLINICAL ... Single-System (Low
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