10 results
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
lymphohistiocytosis (HLH ... IL-1 and IL-6, leading ... is the main clinical ... nervous system (CNS) dysfunction ... Syndrome #Diagnosis #Management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... : fever +++, hepatosplenomegaly ... , Hb), Hepatic dysfunction ... Lymphohistiocytosis #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Lymphohistiocytosis (HLH ... : Overwhelming clinical ... genetic immune dysfunction ... following: • Fever ... Lymphohistiocytosis #diagnosis #management
IDSA Algorithm for the Initial Management of Fever and Neutropenia

LOW RISK
 • Antidpated neutropenia < 7
IDSA Algorithm for ... the Initial Management ... stable and no medical ... #IDSA #Algorithm ... #Management
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... HLH is a critical ... cytopenias and organ dysfunction ... , organ dysfunction ... Clinical Presentation
Shock Classification
Shock Definition: State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Classification ... END-ORGAN DYSFUNCTION ... Hemorrhagic → leading ... Types #diagnosis #management ... warm #wet #dry #table
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... • Dyspnea • Fever ... -95% of cases) Classification ... lymphoma #diagnosis #classification ... hematology #oncology #management
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... Pathophysiology: 1) T-cell dysfunction ... renal failure Clinical ... Self-limiting, chronic but stable ... Sarcoidosis #Diagnosis #Management
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
or family - Ever ... event, follow ACC algorithm ... or LV dysfunction ... Change in clinical ... medical and surgical management
IDSA Algorithm for Neutropenic Fever - Initial Management, Subsequent Management and Prolonged Fever
Figure 1. Initial management
IDSA Algorithm for ... neutropenia < 7 days and clinically ... stable and no medical ... >7 days or • Clinically ... #IDSA #Algorithm